Pep Guardiola rested several of his stars in midweek, as City suffered their first defeat of the season across all competitions against Shakhtar Donetsk in the Champions League. A surprising omission from the starting line up is Sergio Aguero, who sits on the bench, with Gabriel Jesus leading the line. Vincent Kompany and Fernandinho sat out against West Ham in City’s previous league outing, but both return this afternoon.
Manchester City substitutes: Bravo, Danilo, Gundogan, Aguero, Mangala, Bernardo Silva, Zinchenko.
Manchester City (4-3-3): Ederson; Walker, Otamendi, Kompany, Delph; De Bruyne, Fernandinho, Silva; Sterling, Gabriel Jesus, Sane.
Two changes in total from Jose Mourinho compared to the side that started in the dramatic, David De Gea-inspired victory over Arsenal last time out in the league. The suspended Paul Pogba makes way for Ander Herrera in midfield, while Victor Lindelof drops out for Marcus Rashford. In form Jesse Lingard, who netted twice at the Emirates, will be tasked with supporting Romelu Lukaku.
Manchester United substitutes: Lindelof, Jones, Mata, Ibrahimovic, Romero, Shaw, McTominay.
Manchester United (4-2-3-1): De Gea; Valencia, Smalling, Rojo, Young; Herrera, Matic; Martial, Lingard, Rashford; Lukaku.