Tottenham boss Mauricio Pochettino made three alterations to the team that featured in their last league outing, with Davinson Sanchez, Kieran Trippier and Harry Kane making way for Eric Dier, Moussa Sissoko and Ben Davies.
Jose Mourinho decided to make three changes to the United side that started the defeat against Huddersfield, with Eric Bailly, Henrikh Mkhitaryan and Marcus Rashford coming into the starting line-up to replace Juan Mata, Jesse Lingard and Anthony Martial as they switch to a back three.
Tottenham Hotspur substitutes: Vorm, Trippier, Rose, Sanchez, Dembele, N’Koudou, Llorente.
Tottenham Hotspur XI (3-4-2-1): Lloris; Alderweireld, Dier, Vertonghen; Aurier, Sissoko, Winks, Davies; Alli, Eriksen; Son.
Manchester United substitutes: Romero, Darmian, Blind, McTominay, Lingard, Mata, Martial.
Manchester United XI (3-4-1-2): De Gea; Bailly, Smalling, Jones; Valencia, Herrera, Matic, Young; Mkhitaryan; Lukaku, Rashford.
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